Research on New Treatment for Neglected Disease Published in The New England Journal of Medicine
The Institute for OneWorld Health Phase 3 research related to our first approved drug product, Paromomycin IM Injection (Paromomycin), was published in the current issue of The New England Journal of Medicine (NEJM). This clinical trial shows that the medicine paromomycin is safe, effective, and well suited to curing visceral leishmaniasis (VL), the world’s second most deadly parasitic disease after malaria. We are working closely with the Indian Council for Medical Research (ICMR) sponsors of the clinical trial in collaboration with the Special Programme for Research and Training in Tropical Diseases (TDR), a Geneva-based international organization sponsored by UNICEF, UNDP, the World Bank and the World Health Organization. Gland Pharma Limited, the Hyderabad, India-based drug manufacturer, working with OneWorld Health and other collaborators, received regulatory approval from the Drug-Controller General - India (DCGI) for Paromomycin IM Injection as a treatment for VL on August 31, 2006. Gland Pharma has agreed to act as the global manufacturer of Paromomycin to ensure access to all those that need it, and at a markedly reduced cost —currently, approximately $10 USD per 21-day course of therapy. Read the press release.

OneWorld Health’s First Approved Drug Added to WHO Essential Medicines List
Our first approved drug product, Paromomycin IM Injection, was designated by the World Health Organization (WHO) for inclusion on its Model List for Essential Medicines (PDF). Paromomycin IM Injection is a cost-effective treatment for visceral leishmaniasis (VL), the world’s second most deadly parasitic disease after malaria. With approximately 500,000 new cases occurring annually worldwide, visceral leishmaniasis, also known as kala-azar, primarily afflicts the rural poor in India, Nepal, Bangladesh, Sudan and Brazil. The WHO List of Essential Medicines provides a model for countries to select medicines addressing public health priorities. Medicines are selected by the WHO’s Expert Committee on the Selection and Use of Essential Medicines based on its quality, safety and efficacy standards. The WHO List of Essential Medicines helps governments address problems of cost and availability and provides guidance to the pharmaceutical industry on medicine needs globally. Read the press release.

The Institute for OneWorld Health is now on YouTube!
Watch the BBC documentaries featuring iOWH Kill or Cure? kala azar and Kill or Cure? Visceral Leishmaniasis and the Skoll Foundation short movie with Victoria Hale Uncommon Heroes.

Visit YouTube and search for OneWorld Health or go directly to the videos below:
Kill or Cure? kala azar (3 part series)
Kill or Cure? Visceral Leishmaniasis (3 part series)
Uncommon Heroes

Institute for OneWorld Health Now on Giveline -
A Revolutionary Way to Support Our Work
Giveline.com is an online store created for the community-minded shopper, offering more than a million best selling products including books, movies, music, electronics, housewares, gifts and more. Every purchase generates a donation to the Institute for One World Health. The only difference between Giveline and other major online retailers is that every purchase earns money for our organization. Check it out today, and if you decide to buy, remember that Institute for One World Health will earn significant funds in support of our mission.

In addition to the New England Journal of Medicine article Dr. Victoria Hale was quoted in the recent Economist article titled “A Gathering Storm”. Visit our website to read this and other articles about OneWorld Health.

The Institute for OneWorld Health depends on the generous support of individuals all over the world to fulfill our mission. Thank you for supporting our work and helping us to develop and provide access to safe, effective, and affordable medicines for people with neglected diseases in the developing world.

Please consider going to our website now and making a contribution, or calling us at 415.421.4700 for further information.

The Institute for One World Health is growing and searching for passionate and talented industry professionals to help us fulfill our mission of developing safe, effective, and affordable new medicines for people with diseases of poverty in the developing world.

For a current listing of open positions in our San Francisco office please visit the employment page on our website.

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