Institute for OneWorld Health— eNewsletter: January-February 2005


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Institute for OneWorld Health— eNewsletter: January-February 2005



	Announcements and Events

		William Haseltine, Ph.D., Joins OneWorld Health Board of Directors

	OneWorld Health in the News

		San Jose Mercury-News, NPR, Science, Novethic, MedScape

	Science Forum: Issues, Trends and Breakthroughs

	Message from the CEO

	Donor Profile

	Latest Gifts


Spring 2008 Fall 2007 Summer 2007 Kill or Cure? Visceral Leishmaniasis Spring 2007 Winter 2007 Fall 2006 Victoria Hale Named 2006 MacArthur Fellow Paromomycin Injection Approval March/April 2006 January/February 2006 Pipeline November/December 2005 Pipeline September/October 2005 Pipeline July/August 2005 Pipeline May/June 2005 Pipeline March/April 2005 Pipeline January/February 2005 Pipeline November/December 2004 Pipeline September/October 2004 Pipeline July/August 2004 Pipeline May/June 2004 Pipeline Fall 2003 Pipeline

William Haseltine, Ph.D., Joins OneWorld Health Board of Directors.
Recognized worldwide for his work to facilitate better understanding of diseases such as HIV/AIDS and cancer, he is the founder of Human Genome Sciences, Inc. and served as Chairman and Chief Executive Officer from 1993 to Oct. 2004.

In the early 1980s, Dr. Haseltine conducted some of the first research on AIDS, and lobbied and raised funds for a disease many did not want to associate with at that time. He has demonstrated a commitment to social responsibility throughout his career, including his recent work in public service for organizations dedicated to a variety of issues ranging from world economic growth to technology and public policy to creating a national health museum in Washington, D.C. Read the news release >

San Jose Mercury-News, Gates Foundation gives $43 million to fight malaria, Dec 13, 2004
The Bill and Melinda Gates Foundation is expected on Monday to donate $42.6 million to a novel, nonprofit drug company that hopes to make a cheaper malaria treatment by applying a new biotechnology recipe to an ancient Chinese remedy.
Read the article >
NPR, Nonprofit Drug Firm Targets Disease in Third World, Jan 11, 2005.
Hundreds of thousands of people die every year from multiple illnesses that mostly afflict people in the Third World. Unfortunately, drug companies see little profit in researching cures for such diseases. A nonprofit pharmaceutical company is working to change the industry's thinking. NPR's Laura Sydell reports.
Read and listen to the article >
Science, Source of new hope against malaria is in short supply, Jan 7, 2005 (subscription required).
Victoria Hale’s Transformation. Slender, 5-foot-7 with honey-brown ringlets framing her face, Victoria Hale hardly looks like a champion fighter. But the hard-headed scientist and one-time FDA regulator knows how to pack a punch.
Read the article >
Novethic, OneWorld Health : l’entreprise pharmaceutique à but non lucrative.
Read the article >
MedScape, Institute for OneWorld Health – A Not-for-Profit Pharmaceutical Company (webcast video editorial), Jan 7, 2005 (subscription required).
Happy New Year! A good news message to begin 2005.
Read, view, and listen to the article >

Shadow Epidemic: The Growing Menace of Drug Resistance.
Alliance for the Prudent Use of Antibiotics (APUA), Nov. 8, 2004. Shadow Epidemic — the 2005 GAARD Report — for the first time, provides a uniquely comprehensive view of drug resistance patterns across the major infectious diseases. The document focuses on the most troubling and urgent infectious disease threats whose cures are imperiled by antimicrobial resistance: HIV/AIDS, tuberculosis, malaria, gonorrhea, pneumonia, and hospital associated infections. APUA formed the Global Advisory on Antibiotic Resistance Data (GAARD) project in an effort to support and learn from the existing surveillance infrastructure, bringing together the world's largest surveillance systems . Read the report (813kb pdf).

Winter 2005

The tragic consequences of the tsunami in South Asia have riveted the world’s attention, generating a tremendous compassionate response to the immediate needs of the region. The disaster also provides an opportunity to educate people in the west about the everyday disasters in poor regions of the world: diseases such as diarrhea and malaria.

Looking toward the future, the long-term goal for relief efforts should not be to restore people to their previous level of poverty. We need to create real change in health, the kind that heals and strengthens individuals, villages, communities, and eventually, economies and nations.

Addressing global health inequities occurs very slowly. In the past year, OneWorld Health achieved a number of successes, both clinical and organizational, underscoring that a new model for drug development is not only viable, but can thrive. In our fourth year as a nonprofit pharmaceutical company, these are our major accomplishments:

With funds from the Bill & Melinda Gates Foundation, and partners UC Berkeley and Amyris Biotechnologies, we launched a $42.6 million program to use synthetic biology to develop a sustainable and affordable new source of artemisinin-based antimalarials.
Completion of the largest-ever Phase III clinical trial for visceral leishmaniasis
Initial funding to enable a partner, Sanaria, Inc., to evolve the production methods for a novel vaccine for malaria.

We expanded our donor base to include contributions from philanthropic organizations such as the Chiron Foundation, Stanley Thomas Johnson Foundation, Sapling Foundation, and hundreds of individuals from all over the globe. We thank them – and each of you – for your unwavering, continued support.

As we approach our fifth year of operation, I look forward to reaching milestones such as bringing our first new drug to market in India, which is paramomycin for kala-azar; new drug development for pediatric diarrhea; and advances in synthetic biology leading to a fermentation source for antimalarials.

In the coming year will engage a number of pharmaceutical and biotechnology companies to join us in our mission to develop safe, effective, affordable, new drugs for people in the developing world. As a small company, our impact is limited. We need industry’s professionals, their manufacturing and distribution know-how, and most of all, their shared commitment to truly impact global health inequities.

Thank you for believing in us.

Sincerely,

Victoria G. Hale, Ph.D.
CEO and Founder

Number 100: An inspired couple makes a life’s commitment
We were delighted in recent months as so many new friends chose to contribute and we find ourselves humbled by the generosity of people around the world who lend their support, large and small, to our global health efforts. Below is an excerpt of one couple’s letter that inspired us as much as OneWorld Health has inspired them:

Attention Victoria Hale:

I have been a subscriber to Newsweek Magazine for about 5 years, and find it to be mostly ho-hum. Then I read the absolutely eye-popping article about what you and your husband are attempting to accomplish. It is not an idea who’s (sic) time has come: It is an absolutely great idea, and one of the most original, needed, and selfless thoughts of our time. Congratulations!

At present, I donate two times per year each to 99 worthy causes. Not a lot of money: $10 each time, but I would be pleased if you would permit me to make your organization, number 100.

I can’t support you with a more generous offering ($10.00) but I made copies of the Newsweek article, and I’m giving them to all of our friends, neighbors, relatives, bridge club associates, and our Young at Heart Social club.

Personally, my wife and I are both 75 years of age, in relatively good health, and we both recognize what a boon your idea is to those so many humans that are less fortunate than we are.

Enclosed, please find my check in the amount of $10.00, the first of what I hope to continue, twice per year, for as long as I live!

Make a gift today.

Your support enables us to grow, to seek new opportunities and to maintain our leadership as social entrepreneurs in global health. We extend our thanks to the following organizations and individuals for their recent generous gifts:

Corporations, Foundations Amgen Foundation Newsweek Tillin Foundation XYZZY Foundation Individuals Alistair Adams Seema Aghera Karen Alters Largus Angenent Kenneth Baker Andrew Bancroft Andrew Barrett Veronica Barrio Roberta Barrio Hector Barrio Victoria Barrio Will Baumann Barbara Bechler Robert and Kay Bernard Joan and John W. Bernard Sharon Bison Inge Bitter Drs. Terry & Jeanette Blaschke Andy Blue Sean Borzage Kristine Boyden Faye Bremond Harvey & Kathy Brody Lillie Mae Brown Peter Buck Theresa M. Buehler William Buhles Gregory Burgess Alfred Caffiero Metta Cahill Deirdre Campbell Leslie Carr Laura Carr David Carr Frank Carroll Don & Gwen Chandler Ofelia Chang Cathy Cheung Erica Chong Andrew Chu Susan Collier James and Jeanne Collins Ryan Collins Peter Cotton Dr. Shan Crockett Catherine Daly Ruth Darcy Eric Day Kelli Denning Paul & Margie Denning Charles Dexter Toby Dial Albert & Sonia Dorsky Thomas Dupont Steven Dupont Dr. Saul and Tehila Eisenstat John Ellingboe Nancy Eskridge Jenny Everett Hillel & Marjory Fierer Andrew Flake Julia Fox Lee Foster Stephan & Terri Frenkel Howard & Elaine Fromer Dr. Joel Fromer Paul Gardiner Ashok Garg Sigrid Gertsen-Briand Elissa Gilbert Angus Glashier Richard Goldman Timothy Graham Matt Grover Douglas Guarnieri Janet & Joseph Hale Allison Hansen Don & Isabel Harris Nancy & Steve Hazlewood Robert & Mary-Grace Heine Dr. Joseph Heitman Dr. Douglas Henry William Heter Bob & Dale Hill Donald Hill Melissa Hilmes Jim Hinman Jerre & Nancy Hitz Jeff Hoffman Richard & Ellen Hollander Tony Holmes Heather & Gene Hsu Paul Hudnut Jerry Huller Dr. Gerald Hyner Bobbie & Richard Hyman Brigitte Iwaszkiewicz David Jacobus Jenny Jacobus Carol Johnson Jesse Jones Bob & Margaret Jones Galeeb Kachra Sadrudin & Nargis Kachra Audiey Kao Saleem & Yasmin Kassam Hando Kim Suzanne Kim Justine King David Kirby Ashley Kitts Aarti & Asha Kotak Mel & Karen Kronick Charlotte Kuo Janet Lai Miriam Laird Katherine Lapins Jean-Martin Lapointe Rodney Leavitt Paul & Paula Legacki Dr. Helene Lipton Rhoda Lipton D. Todd Littlefield Suzanne Llewellyn		Deanne Loonin Patricia Lowry Catherine Lu Drs. Harold & Lorraine Luft Monica Luke Carolyn Lyon Donald & Kathleen MacHarg Joan MacHarg Kevin MacHarg Skip MacHarg Peter Mays David & Pamela McClellan Michael Mc Grath Janet McAleney Anthony McCandlish Derek & Lani Meek Geoff Miller Jeff Miller Tracy Mills Adam Moliver Daniel Monopoli Wayne Montgomery Victoria Moreno Justin Morgan Maggie Morris Amin Nanji Dr. Richard Nathan Beryl Ness Carol Neufeld Ran Nisbett Dr. Long Ngo Erin O'Neil Karen Oakes Yukari Oka Erin O'Neil Tilda Orr Sara Anne Oudin Anne-Laure Page Barbara Paley Eilene & Michael Peak Allyson Peracca Galen Peracca Cathie & Andy Perga Joyce Pharriss Susan Pilgrim Heike Pope Lawrence & Sandra Post Winnifred Quinn Dawn Reeder Katherine Rensenbrink Eileen Richey Paul Richter Steve Richter Celia Rifkin Arthur & Sue Rinsky Robbin & Gustav Albert & Sonia Rosenblutt David & Judith Rosenblutt Seth Rosenfeld Clifford Rosky Mariana Roytman Frederick Rudolph Joanne Sabella Kelly Saffrey Brian Sales Alida K. Samuels Jessica Sanfilippo John & Diane Savage Carol Savio John & Maria Schipper Linda Schmidt Kirsten Schmidt Leah Schoellkopf Donna Seid Dr. Theresa Shapiro Karla Shepard Rubinger Ronald A. Siegel Noreen Silver Julie Simpson Joyce & Ken Smith Ellen Snee Dr. Joseph Snow Ilene Sokoloff Robert & Patricia Spear C. Edward & Shondell Spiegel Ingrid Stabb Carol & Robert Stevenson Deanne Stewart Valerie Stinger Christopher Stirling Carrie Stricker James Stricks Thomas Strohl Veronica Stuzka Andrea Sullivan Catherine Sweeny Joan Swenson Ken & Audrey Tabon Michael Taborn Neomi Taborn Tricia Taborn Theresa Thadani Randall Thomas John D. Thomas Francesca Tillman Risa Torkin Matthew Triska Helen Yen Yun Chang Tsui David Turnipseed Anshu Vashishtha Sarah Vidal Janet Walter Jordan Walters Nathan Walters Ralph Wheeler John Whitman Dan Wilkowsky Judith William Ronald Williams Allen & Jean Wolman Dana Woods Grace Yokoi Juliana Youn Buffy Young Maeme Young Ulana Zakalak

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